On the Back Cover
Chemical biology is a rapidly growing and exciting interdisciplinary science, combining chemical tools for the study of biological problems and the development of innovative solutions that would not be possible by applying methodology from one field only.
This first book to adopt a problem-based approach teaches the true basics of the subject by way of illustrated case studies. The editor's extensive experience in chemical biology education and their close relationship to the authors ensure that the contributions here are presented in a pedagogically uniform and highly motivating fashion.
From the contents:
* Ras Proteins, Synthesis, Ras Cycle, Biochemistry
* Proteases, Proteasome
* Activity-Based Proteomics
* FK506
* Regulation of Gene Expression, Transcription
* Protein Synthesis, Native Chemical Ligation
* Expressed Protein Ligation
* Microarray Technologies
* APT1, Ras Palmitoylation
* Carbohydrates
* Yeast Based Chemical Genomics
* Target Identification
* BIOS, PSSC, Natural Products
* Alzheimer
* Diversity Oriented Synthesis
* Kinases, Orthogonal Chemical Genetics
Each chapter introduces a different biological problem, so that students learn how to think in order to solve problems in biology by using powerful techniques and tools taken from chemistry.
