Completely revised and updated since publication of the highly-valued first edition in 2002, the Oxford Textbook of Endocrinology and Diabetes second edition provides an up-to-date, stimulating and comprehensive account of endocrinology and diabetes. Containing first rate, pragmatic advice on diagnosis and clear guidelines for recommended management, it also covers the scientific principles that underlie medical practice. Packed into one comprehensive volume, the textbook contains 254 chapters, organised into 13 sections for easy-access to the relevant information. Each chapter is written by an internationally-acknowledged expert, relates basic science to evidence based guidelines and clinical management, and where appropriate offers an outline of the controversies in the field. The textbook has an international focus, and where possible deals with medical practice in countries without advanced medical resources. Containing over 700 illustrations, including a colour plate section of 100 full colour photographs, and numerous tables and boxes to complement the text, the textbook is now also available online. Individuals who purchase the print edition of the Oxford Textbook of Endocrinology and Diabetes second edition are entitled to six months free access to the online version. Features Contains 254 chapters, organised into 13 sections, covering all aspects of endocrinology and diabetes Includes over 700 illustrations, plus a colour plate section of 100 full-colour photographs, and numerous tables and boxes to complement the text Written by a team of over 300 international experts Relevant for trainees and experienced practitioners alike Complemented by a fully-searchable online version, available free for six months to individuals who purchaser the book Completely updated and revised since publication of the first edition in 2002 Now in two-colour Further algorithms and flowcharts have been added to ensure easy access to management information, while more figures, tables and boxes have been included throughout the book Increased clinical management advice Contains a new section on the endocrinology of cancer Table of Contents Principles of international endocrine Practice 1.1. A history of endocrinology 1.2. Prevention in endocrinology 1.3. Endocrinology and evolution: lessons from comparative endocrinology 1.4. Hormones and receptors: fundamental considerations 1.5. Molecular basis of hormonal action 1.6. Endocrine autoimmunity 1.7. Measurement of circulating hormones 1.8. Endocrine disruptors 1.9. Sports endocrinology Pituitary and hypothalmic diseases 2.1. Pituitary anatomy and physiology 2.2. The neurohypophysis 2.3. Aetiology, pathogenesis, and management of disease of the pituitary 2.4. Aetiology, pathogenesis, and management of disease of the hypothalamus 2.5. Pineal physiology and pathophysiology including pineal tumours 2.6. Neuropsychiatric endocrinological disorders The thyroid 3.1. Evaluation of the thyroid patient 3.2. Aetiology of thryroid disorders 3.3. Thyrotoxicosis and related disorders 3.4. Hypothyroidism and pregancy- and growth-related thyroid disorders 3.5. Thyroid lumps Parathyroid, calcium and bone metabolism 4.1. Parathyroid anatomy, hormone synthesis, secretion, action, receptors 4.2. Hypercalcaemia 4.3. Primary hyperparathyroidism 4.4. Familial hypocalciuric hypercalcaemia 4.5. Hypocalcaemic disorders, hypoparathyroidism, and pseudohypoparathyroidism 4.6. Hypercalcaemic and hypocalcaemic syndromes in children 4.7. Osteoporosis 4.8. Thyroid disease and osteoporosis 4.9. Pagets disease of bone 4.10. Rickets and osteomalacia (acquired and heritable forms) and skeletal dysplasias 4.11. Glucocorticoid induced osteoporosis The adrenal gland and endocrine hypertension 5.1. Adrenal imaging 5.2. Adrenal surgery 5.3. Adrenal incidentaloma 5.4. Adrenocortical cancer 5.5. Phaeochromocytomas, paragangliomas, and neuroblastoma 5.6. Primary aldosteronism and other steriod-related causes of endocrine hypertension 5.7. Cushings syndrome 5.8. Glucocorticoid resistance - the defect in glucocorticoid receptor 5.9. Addisons disease (adrenal insufficiency) 5.10. Familial glucocorticoid deficiency syndromes- the defect ACTH receptor 5.11. Congenital adrenal hyperplasia Neuroendocrine tumours and genetic disorders 6.1. An appraisal of the past and perspectives for the future 6.2. Neuroendocrine tumour markers 6.3. Neuroendocrine (carcinoid) tumours and the carcinoid syndrome 6.4. Gastrinoma 6.5. Insulinomas and hypoglycaemia 6.6. Glucagonoma 6.7. VIPomas 6.8. Somatostatinomas 6.9. Imaging neuroendocrine tumours of the gastrointestinal tract 6.10. Mastocytosis 6.11. MEN1 6.12. MEN2 6.13. Von Hippel-Lindau disease and succinate dehydrogenase subunit (SDHB, SDHC and SDHD) genes 6.14. Neurofibromatosis 6.15. Carneys complex 6.16. Molecular and clinical characteristics of McCune Albrights syndrome 6.17. Cowdens syndrome Growth and development during childhood 7.1. Normal growth and sexual development 7.2. Growth and sexual disorders in childhood Female endocrinology and pregnancy 8.1. Female endocrinology and ovarian disorders 8.2. Pregancy-related disorders Male endocrinology 9.1. Definitions and classifications of disorders 9.2. Normal male endocrinology 9.3. Evaluation of the male patient with suspected endocrinological disease 9.4. Male endocrinological disorders and male factor infertility 9.5. Exogenous factors and male reproductive health Endocrinology of ageing and systemic disease 10.1. Ageing and the endocrine system 10.2. Endocrinology of systemic disease Endocrinology of cancer 11.1. Secondary endocrine tumours, ectopic hormone syndromes, and effects of cancer treatment on endocrine function 11.2. Hormonal therapy for breast and prostatic cancers Obesity, lipids and metabolic disorders 12.1. Epidemiology, aetiology, and management of obesity 12.2. Lipoprotein metabolism and related diseases 12.3. Other metabolic disorders Diabetes mellitus 13.1. Diagnosis and classification of diabetes mellitus 13.2. Aetiology and pathogenesis of type 1 diabetes mellitus 13.3. Aetiolology and pathogenesis of type 2 diabetes mellitus 13.4. Management of diabetes mellitus 13.5. Microvascular complications 13.6. Macrovascular diseases and diabetes mellitus 13.7. The diabetic foot 13.8. Mental health in diabetes mellitus 13.9. Organisation of diabetes care
